The WTO Annual Report 2022 provides a comprehensive account of the WTO's activities in 2021 and early 2022. It also covers the 12th Ministerial Conference (MC12), originally scheduled for end-2021 but postponed until June 2022. The Report opens with a message from Director-General Ngozi Okonjo-Iweala, who looks back at the successful conclusion of MC12, the role of the WTO in addressing COVID-19 and the challenges facing world trade. This is followed by an overview of the WTO's activities in 2021 and early 2022, a snapshot of MC12 and in-depth accounts of the WTO's main areas of activity.